Carious lesion dynamics are dependent predominantly on the availability of fermentable sugars other environmental conditions bacteria and host factors our current understanding of the microorganisms involved in the initiation and progression of caries is still rather incomplete the most relevan . Suggested citationpathology of dental cariesnational research council 1952 a survey of the literature of dental carieswashington dc the national academies press doi 1017226 21295. Dentinal caries dentine can be affected both pre cavitation and post cavitation of the lesion unlike enamel the presence of alive odontoblasts allows for reparative and protective changes to occurdue to lateral spread at the adj a larger cavity can form very quickly particularly larger than the apparent enamel lesion. Dental caries dental caries is an irreversiblemicrobial disease of the calcifiedtissues of the teeth characterizedby de mineralisation of inorganicportion and destruction of organicsubstance of the tooth which oftenleads to cavitationshafers textbook of oral pathology 6th edition 4
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